Myeloperoxidase gene-463G > a polymorphism and premature coronary artery disease
نویسندگان
چکیده
منابع مشابه
Myeloperoxidase gene-463G > A polymorphism and premature coronary artery disease
We investigated the association between myeloperoxidase gene -463G > A polymorphism and premature coronary artery disease (CAD) in two Chinese population samples: 229 patients and 230 controls. Genotypes were determined by ligase detection reaction-polymerase chain reaction sequencing and the grouping technique. We found lower frequencies of both the A/A genotype and the A allele in patients (p...
متن کاملPRISMA-combined Myeloperoxidase -463G/A gene polymorphism and coronary artery disease
BACKGROUND Myeloperoxidase (MPO) -463G/A gene polymorphism may be associated with an increased risk of developing coronary artery disease (CAD). Studies on the subject, however, do not provide a clear consensus. This meta-analysis was performed to explore the relationship between MPO gene -463G/A polymorphism and CAD risk. METHODS This meta-analysis combines data from 4744 subjects from 9 ind...
متن کاملMyeloperoxidase polymorphism and coronary artery disease risk
The myeloperoxidase (MPO) gene 463G/A and 129G/A polymorphisms have been reported to be associated with coronary artery disease (CAD), but the results remain inconclusive. This meta-analysis was designed to clarify these controversies.PubMed, EMBASE, and the Cochrane Library were used to retrieve the relevant literature up to March 2015 according to keywords. A total of 8 case-control studies, ...
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ژورنال
عنوان ژورنال: Genetics and Molecular Biology
سال: 2009
ISSN: 1678-4685,1415-4757
DOI: 10.1590/s1415-47572009005000035